[Benign metastasizing uterine leiomyoma: case reports]. / Leiomioma uterino metastatizante benigno: relato de dois casos.

Benign metastasizing leiomyomatosis (BML) is a rare disease in which the lung is the most affected extra-uterine organ. The BML histology is compatible with benignity and similar to that found in the myometrial leiomyoma. A history of surgically treated uterine myomatosis is reported by most of the patients with metastatic disease. We report the cases of two patients with uterine metastasizing leiomyomatosis. In the first case, a 55-year-old patient presented lung nodes over 20 years after being submitted to hysterectomy due to uterine leiomyoma. The histological and immunohistochemical studies from the lung node revealed that it was an implant of benign leiomyoma. The second patient, a 65-years-old woman, presented lung and retroperitoneal nodes 20 years after being submitted to a hysterectomy due to uterine leiomyoma.

Leiomioma uterino metastatizante benigno: relato de dois casos / Benign metastasizing uterine leiomyoma: case reports

Leiomiomatose metastatizante benigna (LMB) é uma doença rara na qual o pulmão é o órgão extrauterino mais afetado. A histologia da LMB é compatível com benignidade e semelhante à encontrada nos leiomiomas miometriais. Uma história de miomatose uterina tratada cirurgicamente é relatada por quase todas as pacientes com a doença metastática. Relatamos dois casos de pacientes com leiomiomatose uterina metastatizante. No primeiro caso, uma paciente de 55 anos de idade apresentou nódulos pulmonares mais de 20 anos após ter sido submetida a uma histerectomia por leiomioma uterino. Os estudos histológico e imunoistoquímico do nódulo pulmonar revelaram tratar-se de implante de leiomioma benigno. A segunda paciente, de 65 anos de idade, apresentou nódulos pulmonares e retroperitoneais 20 anos após ter sido submetida a uma histerectomia em razão de um leiomioma uterino.

Benign metastazing leiomyomatosis (BML) is a rare disease in which the lung is the most affected extra-uterine organ. The BML histology is compatible with benignity and similar to that found in the myometrial leiomyoma. A history of surgically treated uterine myomatosis is reported by most of the patients with metastatic disease. We report the cases of two patients with uterine metastazing leiomyomatosis. In the first case, a 55-year-old patient presented lung nodes over 20 years after being submitted to hysterectomy due to uterine leiomyoma. The histological and immunohistochemical studies from the lung node revealed that it was an implant of benign leiomyoma. The second patient, a 65-years-old woman, presented lung and retroperitoneal nodes 20 years after being submitted to a hysterectomy due to uterine leiomyoma.